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Escort Oxidative burden Hydroxyacetanilide patterns of protein adduction, 103 difficulty in favour of covalent binding theory, 102 Hydroxyethyl radicals, 266 Hydroxynonenal contribution to drunk steatosis in mice, 273 shape during demon rum intoxication, 266 institution during lipid peroxidation, 111 Hypersensitivity toxicity, role of invulnerable mechanisms, 43 Hypothesis-free fact-finding, enabled close to omics technology, 119 I Idiosyncratic toxicity, ALDH2 polymorphisms and john barleycorn warmth, 41 Insusceptible system team pathway involvement in lush liver malady, 270 complex roles in swelling condition, 227 impersonation in drinker liver malady, 270 part in asbestosis, 254 responsibility in paracetamol hepatoxicity (innate), 165 situation of adaptive unsusceptible feedback in alcohol toxicity, 271 Inositol requiring enzyme-1 (IRE1) activation pathway, 145 situation in ER accent reaction, 145 Cosmopolitan Intermediation in the service of Study on Cancer (IARC) friendship of non-lung cancer wiuth smoking, 294 carcinogen classification system, 246 Interstitial nephritis, 179 Isoprostanes, biomarkers of lipid peroxidation, 111 Isotretinoin, 199 J Jaundice, hyperbilirubinemia in alcoholic liver disability, 274 K Keap1, 141 Kidney(s) basic systematize and functions, 176 factors predisposing to toxicity, 176 injury by trichloroethylene, 184 post in xenobiotic excretion, 83 Kidney injury marker-1 (KIM-1) urinary marker of kidney damage, 180 use in trichlorethylene users, 185 Kupffer cells basic features, 158 r“le in drunk liver bug, 270 L Take, 9 nearness in tobacco smoke, 298 Legislative initiatives Chemical Substances Check Law (Japan), 19 Index The using software is effort version. 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